Know More About Von Hippel–Lindau Disease, and How we Can Fix It
Know More About Von Hippel–Lindau Disease, and How we Can Fix It: Von Hippel–Lindau disease (VHL), is a rare genetic disorder with multisystem involvement. It is described by visceral cysts and benign tumors with potential for consequent malignant transformation. It is also known as familial cerebello retinal angiomatosis. It is a type of phakomatosis that results from a mutation in the von Hippel–Lindau tumor suppressor gene on chromosome 3p25.3. The disease is similarly categorized by an increased risk of developing the following types of tumors: · Hemangioblastomas of the central nervous system - Benign (noncancerous) tumors made up of nests of blood vessels in the brain and spine · Hemangioblastomas of the retina · Pheochromocytomas – A neuroendocrine tumor, typically benevolent, inside or outside of the adrenal gland · Renal cell carcinoma - Cancerous tumor of the kidney that arises in about 70 percent of individuals with V