6th International Conference on Rare Diseases and Orphan Drug

Xia-Gibbs syndrome is a recently discovered Rare Genetic Disorder that is initiated by a heterozygous mutation in the AHDC 1 gene on Chromosome 1p36 .So it is ultimately known as AHDC1-related intellectual disability-obstructive sleep apnea-mild dysmorphism syndrome . Affected people usually present with developmental delay, low muscle tome, failure to thrive, breathing difficulties when sleeping, mildly unusual facial features. Symptoms:   Symptoms of Xia-Gibbs Syndrome include, ·          Expressive language skills are particularly affected; children with this condition usually do not speak their first word, a milestone typically achieved within the first year, until age two or later, and some never learn to talk. ·          Development of motor skills, such as crawling and walking, can also be delayed. ·          Other signs and symptoms of...

The truth about severe PTSD identification by brain marker is about to be revealed: Post-Traumatic Stress Disorder is an anxiety disorder that can develop in response to a stressful event or situation of exceptionally threatening or catastrophic nature. It usually develops followings a single episode of trauma . Patients have the capacity to forget but in complex PTSD case they will get flashbacks and nightmares associated with insomnia from time to time. It is associated with behavioural issues and reckless activities like binge eating, abnormal sexual activities and drug and alcohol abuse. Although its diagnostic features have been recently re-classified with the emergence of the Diagnostic and Statistical Manual for Mental Disorders, it remains characterized by hyperarousal, intrusive reminders of the trauma, prevention of trauma-related indications, and negative cognition and mood. This heterogeneity specifies the presence of multiple neurobiological mechanisms und...